RNA-polymerase is a molecular machine that bindes to specific DNA sequences marking the begining of genes. After binding, it satrts synthesizing RNA according to the genetic code in DNA in a process called gene expression. This image shows several genomes of the virus T7 that were stretched on glass and labeled with a fluorescent dye (Blue lines). The colored spots along the DNA are fluorescent quantum dots that were designed to target the T7-RNA polymerase, allowing us to find their binding position along the genome. Different binding proteins can be targeted by quantum-dots with differnt fluorescent color in order to distinguish between them and understand the relationships between their binding events.Click here for a little feature article about some of the work I've been doing to optically map RNA polymerase on the genome of the T7 virus
Hi, I'm Yuval Ebenstein and Since August 2011 I have been leading the NanoBioPhotonics research group in Tel-Aviv university. We explore some exciting biological systems utilizing tools and reagents from the realm of nano-technology. We try learning new things about these systems by zooming in on individuals - single cells, single chromosomes and single molecules.
Research in the lab is highly multi and inter disciplinary and our team is composed of chemists, biologists and physicists who are interested in learning from each other and doing some great (but sometimes risky...) stuff at the very forefront of science. I'll try updating news here as well but....
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